Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539833 | 0.84 | NFE2L2 (0.43) | ALDH1A1HCAR2NAAAMAPT | |
| SCHEMBL8539829 | 0.84 | NFE2L2 (0.43) | ALDH1A1HCAR2NAAAMAPT | |
| SCHEMBL9586348 | 0.80 | NAAA (0.51) | ALDH1A1NAAATSHRMAPT | |
| SCHEMBL4812064 | 0.79 | NAAA (0.47) | NAAAMAPT | |
| SCHEMBL4812060 | 0.79 | NAAA (0.47) | NAAAMAPT | |
| SCHEMBL4970993 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNA | |
| SCHEMBL4970985 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNA | |
| SCHEMBL4970673 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HCAR2MAPTLMNA | |
| SCHEMBL4970676 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HCAR2MAPTLMNA | |
| SCHEMBL4806247 | 0.76 | NAAA (0.44) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262299-B2 | Diels-Alder reaction; using zeolite y in exchanged with copper; separated from mixture for reuse | JOHNSON MATTHEY PLC (GB) | 2007-08-28 | — | — | US | disclosed |
| US-7262299-B2 | Diels-Alder reaction; using zeolite y in exchanged with copper; separated from mixture for reuse | JOHNSON MATTHEY PLC (GB) | 2007-08-28 | — | — | US | disclosed |