Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GPR39 | O43194 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025837 | 0.88 | GRM5 (0.43) | GRM5FFAR1KDM4ETSHRMAPK1 | |
| SCHEMBL10368628 | 0.80 | GRM5 (0.39) | GRM5FFAR1KCNH2KDM4ETSHR | |
| SCHEMBL10369402 | 0.78 | KCNH2 (0.47) | GRM5KCNH2 | |
| SCHEMBL14732908 | 0.77 | CCR1 (0.42) | GRM5FFAR1KCNH2 | |
| SCHEMBL9024906 | 0.76 | GRM5 (0.44) | GRM5FFAR1GPR39 | |
| SCHEMBL9500899 | 0.75 | BRD4 (0.41) | GRM5FFAR1KCNH2 | |
| SCHEMBL9027236 | 0.75 | FFAR1 (0.40) | GRM5FFAR1KDM4ETSHRMAPK1 | |
| SCHEMBL14733157 | 0.74 | GRM5 (0.44) | GRM5FFAR1KCNH2 | |
| SCHEMBL9025927 | 0.73 | GRM5 (0.38) | GRM5FFAR1TSHR | |
| SCHEMBL15470589 | 0.73 | CCR1 (0.60) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208239-A | Plant fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-04 | — | — | US | disclosed |