Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | GPR39 | O43194 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586353 | 0.88 | GRM5 (0.42) | GRM5FFAR1MAPK1GPR39DYRK1A | |
| SCHEMBL9500899 | 0.87 | BRD4 (0.41) | GRM5FFAR1RAB9ASMN1; SMN2 | |
| SCHEMBL9027236 | 0.86 | FFAR1 (0.40) | GRM5FFAR1MAPK1RAB9AKMT2A | |
| SCHEMBL9024906 | 0.83 | GRM5 (0.44) | GRM5FFAR1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL9025927 | 0.80 | GRM5 (0.38) | GRM5FFAR1TSHR | |
| SCHEMBL9550832 | 0.76 | CCR1 (0.43) | GRM5FFAR1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9026730 | 0.76 | ROCK1 (0.43) | GRM5RAB9A | |
| SCHEMBL10368628 | 0.76 | GRM5 (0.39) | GRM5FFAR1KDM4ETSHR | |
| SCHEMBL9026091 | 0.75 | FFAR1 (0.44) | GRM5FFAR1MAPK1KMT2ATDP1 | |
| SCHEMBL9586361 | 0.75 | GRM5 (0.42) | GRM5FFAR1MAPK1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459662-B1 | Fungicidal compounds | ZENECA LTD (GB) | 1996-08-21 | — | — | EP | disclosed |
| US-5185339-A | FUNGICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0459662-A1 | Fungicidal compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |