Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542205 | 0.91 | TSHR (0.43) | POLBKMT2AMAPTTSHRMEN1 | |
| SCHEMBL9541782 | 0.88 | KMT2A (0.41) | MAPK1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL9542171 | 0.86 | GAA (0.46) | POLBKMT2AMAPTTSHRMEN1 | |
| SCHEMBL9543471 | 0.85 | MEN1 (0.42) | MAPK1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL9541760 | 0.80 | TUBB4A (0.51) | POLBKMT2AMAPTMEN1SLC6A9 | |
| SCHEMBL9542198 | 0.79 | GAA (0.47) | KMT2AMAPTTSHRMEN1CYP1A2 | |
| SCHEMBL9540822 | 0.78 | THRB (0.46) | POLBKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL9584306 | 0.77 | SLC6A9 (0.44) | POLBMAPK1KMT2AALDH1A1MAPT | |
| SCHEMBL9542307 | 0.77 | MEN1 (0.42) | POLBKMT2AALDH1A1MAPTTSHR | |
| SCHEMBL9542195 | 0.77 | MEN1 (0.40) | POLBKMT2AALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |