Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587742 | 0.92 | ALDH1A1 (0.39) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL9587480 | 0.92 | FNTA (0.38) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL9588746 | 0.91 | CDK2 (0.40) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL9587389 | 0.86 | AR (0.41) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL9586729 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL9585879 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL9588516 | 0.83 | GHSR (0.35) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL9587907 | 0.83 | MAPT (0.37) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL9587904 | 0.82 | AR (0.41) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL9588176 | 0.81 | CDK2 (0.50) | ALDH1A1MAPTGAAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018030-A1 | BENZIMIDAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-16 | — | — | WO | disclosed |