Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.50 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | DNA2 | P51530 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588746 | 0.85 | CDK2 (0.40) | CDK2GAAMAPTALDH1A1KMT2A | |
| SCHEMBL9587152 | 0.81 | ALDH1A1 (0.39) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9587742 | 0.80 | ALDH1A1 (0.39) | CDK2GAAMAPTALDH1A1KMT2A | |
| SCHEMBL9587480 | 0.80 | FNTA (0.38) | CDK2GAAMAPTALDH1A1MEN1 | |
| SCHEMBL9239153 | 0.78 | CDK2 (0.51) | CDK2TSHRGAAMAPTALDH1A1 | |
| SCHEMBL9587907 | 0.76 | MAPT (0.37) | CDK2GAAMAPTALDH1A1KMT2A | |
| SCHEMBL9588516 | 0.76 | GHSR (0.35) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9587389 | 0.74 | AR (0.41) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9586729 | 0.73 | ALDH1A1 (0.39) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL15221815 | 0.73 | AR (0.40) | GAAMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018030-A1 | BENZIMIDAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-16 | — | — | WO | disclosed |