Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.35 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.35 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.35 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.35 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.35 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.35 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586338 | 0.89 | LMNA (0.39) | LMNATSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL9587635 | 0.87 | LMNA (0.42) | LMNAFPR1MMP12PSMB11PSMA7 | |
| SCHEMBL9587330 | 0.87 | SLC6A2 (0.41) | LMNATSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL9588164 | 0.84 | LMNA (0.40) | LMNAFPR1HTR1ADRD2MMP12 | |
| SCHEMBL9588229 | 0.80 | LMNA (0.43) | LMNATSHRFPR1POLBHTR1A | |
| SCHEMBL9586748 | 0.78 | LMNA (0.47) | LMNATSHRFPR1POLBHTR1A | |
| SCHEMBL10435319 | 0.78 | LMNA (0.35) | LMNAFPR1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL24202741 | 0.78 | CYP2E1 (0.39) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9589256 | 0.77 | TDP1 (0.45) | — | |
| SCHEMBL9588340 | 0.77 | TDP1 (0.49) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | claimed |
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0383950-A1 | PYRIDINE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |