Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587199 | 0.89 | LMNA (0.43) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9587330 | 0.87 | SLC6A2 (0.41) | LMNASLC6A2SLC6A4SLC6A3TBXAS1 | |
| SCHEMBL9586839 | 0.79 | RIPK1 (0.40) | LMNASLC6A2SLC6A4SLC6A3TRPA1 | |
| SCHEMBL27335859 | 0.78 | AOC1 (0.41) | LMNACYP3A4CYP2D6CYP2A6 | |
| SCHEMBL9588340 | 0.77 | TDP1 (0.49) | TBXAS1MEN1KMT2A | |
| SCHEMBL9589256 | 0.77 | TDP1 (0.45) | TBXAS1 | |
| SCHEMBL9846137 | 0.77 | CYP2E1 (0.34) | LMNACYP3A4CYP2D6CYP2A6 | |
| SCHEMBL9588164 | 0.76 | LMNA (0.40) | LMNASLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL9587635 | 0.76 | LMNA (0.42) | LMNAALDH1A1 | |
| SCHEMBL9588159 | 0.76 | LMNA (0.40) | LMNASLC6A2SLC6A4SLC6A3TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | claimed |
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| US-5256670-A | N-aryl-3-aryl-4-substituted-2,3,4,5-tetrahydro-1H-pyrazole-1-carboxamides, insecticidal compositions containing such compounds and methods of controlling insects such compounds | ROHM AND HAAS COMPANY (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0490569-A1 | N-aryl-3-aryl-4-substitued-2,3,4,5-tetrahydro-1H-pyrazole-1-carboxamides and methods of their production | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| US-5109014-A | Useful as insecticide or pesticide | DOW AGROSCIENCES LLC, A DELAWARE LIMITED LIABILITY COMPANY | 1992-04-28 | — | — | US | disclosed |
| EP-0383950-A1 | PYRIDINE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |