Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.37 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.37 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.37 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.37 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587199 | 0.87 | LMNA (0.43) | LMNAMMP12SMN1; SMN2FPR1PSMB11 | |
| SCHEMBL9588164 | 0.83 | LMNA (0.40) | LMNAMMP12SMN1; SMN2L3MBTL1FPR1 | |
| SCHEMBL9587330 | 0.80 | SLC6A2 (0.41) | LMNAALDH1A1 | |
| SCHEMBL9589256 | 0.76 | TDP1 (0.45) | L3MBTL1KDM6BKDM4C | |
| SCHEMBL9588340 | 0.76 | TDP1 (0.49) | L3MBTL1KDM6BKDM4C | |
| SCHEMBL9586338 | 0.76 | LMNA (0.39) | LMNAALDH1A1 | |
| SCHEMBL24434614 | 0.76 | HTR1A (0.45) | L3MBTL1KDM6BKDM4CALDH1A1 | |
| SCHEMBL9589128 | 0.75 | TDP1 (0.47) | L3MBTL1KDM6BKDM4C | |
| SCHEMBL9588643 | 0.75 | TDP1 (0.47) | L3MBTL1KDM6BKDM4C | |
| SCHEMBL9587577 | 0.75 | TDP1 (0.47) | L3MBTL1KDM6BKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0383950-A1 | PYRIDINE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |