Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 9/20 | 0.35 |
| ▸ | PPOX | P50336 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587505 | 0.86 | SLC6A9 (0.33) | SLC6A9F10SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9590341 | 0.85 | GFER (0.36) | — | |
| SCHEMBL9587001 | 0.84 | CA1 (0.39) | PGR | |
| SCHEMBL9589242 | 0.84 | CA1 (0.39) | S100A4F10MAPT | |
| SCHEMBL9589861 | 0.82 | ALDH1A1 (0.42) | MAPT | |
| SCHEMBL9590296 | 0.82 | CA1 (0.43) | F10MAPT | |
| SCHEMBL9588974 | 0.81 | KMT2A (0.42) | MAPT | |
| SCHEMBL9588325 | 0.81 | ABCC9 (0.41) | F10MAPT | |
| SCHEMBL6369766 | 0.81 | ABCC9 (0.50) | F10PGR | |
| SCHEMBL9587437 | 0.81 | ABCC9 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5272170-A | Tetralones with pharmacological activity | J. URIACH & CIA., S.A. (ES) | 1993-12-21 | — | — | US | disclosed |
| US-5208246-A | Hypotensive, bronchodilator | J. URIACH & CIA. (ES) | 1993-05-04 | — | — | US | disclosed |
| EP-0489300-A2 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1992-06-10 | — | — | EP | disclosed |