Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2211175 | 0.78 | HTT (0.41) | GAAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9762512 | 0.78 | ALDH1A1 (0.41) | GAAALDH1A1MAPTCYP3A4TSHR | |
| SCHEMBL10781893 | 0.77 | ALDH1A1 (0.43) | GAAALDH1A1MAPTCYP3A4TSHR | |
| SCHEMBL8673993 | 0.75 | HTT (0.32) | GAASMN1; SMN2RAB9AHTT | |
| SCHEMBL25063183 | 0.75 | MAPT (0.39) | GAAALDH1A1MAPTCYP3A4TSHR | |
| SCHEMBL375913 | 0.75 | ALDH1A1 (0.42) | GAAALDH1A1MAPTCYP3A4TSHR | |
| SCHEMBL27671733 | 0.75 | MAPT (0.39) | GAAALDH1A1MAPTCYP3A4TSHR | |
| SCHEMBL19435550 | 0.75 | LMNA (0.41) | GAAALDH1A1MAPTCYP3A4TSHR | |
| SCHEMBL28510882 | 0.75 | ALDH1A1 (0.41) | GAAALDH1A1MAPTCYP3A4TSHR | |
| SCHEMBL9761304 | 0.75 | GAA (0.37) | GAAALDH1A1MAPTCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683903-B | Thiazole heterocycle azo type reactive dye and preparation method thereof | 青岛理工大学 | 2024-03-15 | — | — | CN | claimed |
| CN-117004183-A | Halogen-free flame-retardant resin composite material and preparation method thereof | 合肥乾润钢塑有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-113683903-A | Thiazole heterocyclic azo type reactive dye and preparation method thereof | 青岛理工大学 | 2021-11-23 | — | — | CN | claimed |
| US-4496727-A | ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | claimed |
| US-4385174-A | FOR PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | claimed |
| US-4349671-A | Process for the production of metal complexes of isoindoline azines | CIBA-GEIGY CORPORATION (US) | 1982-09-14 | — | — | US | claimed |
| JP-55052352-A | — | — | None | — | — | JP | disclosed |
| CN-113683903-B | Thiazole heterocycle azo type reactive dye and preparation method thereof | 青岛理工大学 | 2024-03-15 | — | — | CN | disclosed |
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
| CN-117004183-A | Halogen-free flame-retardant resin composite material and preparation method thereof | 合肥乾润钢塑有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-113683903-A | Thiazole heterocyclic azo type reactive dye and preparation method thereof | 青岛理工大学 | 2021-11-23 | — | — | CN | disclosed |
| EP-3442952-A1 | METHODS OF TREATMENT OF CHOLESTASIS AND FIBROSIS | Genfit (FR) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017178174-A1 | METHODS OF TREATMENT OF CHOLESTASIS AND FIBROSIS | GENFIT (FR) | 2017-10-19 | — | — | WO | disclosed |
| US-3954398-A | Polyester fibers dyed with a disazo disperse dyestuff | CIBA-GEIGY AG (CH) | 1976-05-04 | — | — | US | disclosed |
| US-3950130-A | THIAZOLE-AZO DYES AND THE COLORATION OF POLYESTER TEXTILE FIBERS THEREWITH | AMERICAN ANILINE PRODUCTS, INC. (US) | 1976-04-13 | — | — | US | disclosed |
| US-3950321-A | POLYESTERS | BASF AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
| US-3945989-A | Fluoro triazine containing water insoluble azo dyestuff | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |
| US-3945991-A | Heterocyclic azo compounds containing a quaternated hydrazide group | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |
| US-3943120-A | WATER INSOLUBLE | CIBA-GEIGY AG (CH) | 1976-03-09 | — | — | US | disclosed |
| US-3933786-A | Heterocyclic-azo-phenyl compounds containing a styrl group | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | NOS1 4425/4885GAA 2196/4885ALDH1A1 1427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.