Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298881 | 0.85 | MME (0.58) | MMECYP3A4MAPK1NPC1RAB9A | |
| SCHEMBL9588793 | 0.85 | CYP3A4 (0.46) | MMECYP3A4MAPK1NPC1RAB9A | |
| SCHEMBL7450894 | 0.84 | MME (0.52) | MMECYP3A4MAPK1NPC1RAB9A | |
| SCHEMBL8837469 | 0.84 | FCER2 (0.50) | MMECYP3A4MAPK1NPC1RAB9A | |
| SCHEMBL9587977 | 0.84 | KMT2A (0.59) | MMENPC1RAB9AOPRK1 | |
| SCHEMBL7435110 | 0.84 | MME (0.46) | MMECYP3A4MAPK1NPC1RAB9A | |
| SCHEMBL9068533 | 0.83 | MME (0.62) | MMECYP3A4MAPK1PAMACE | |
| SCHEMBL7304584 | 0.83 | MME (0.46) | MMECYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9588619 | 0.82 | CYP3A4 (0.54) | MMECYP3A4MAPK1NPC1RAB9A | |
| SCHEMBL9587952 | 0.82 | MME (0.47) | MMECYP3A4MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190974-A | Analgesics | ROUSSEL UCLAF (FR) | 1993-03-02 | — | — | US | disclosed |