Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 4/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 4/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589274 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL9589282 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL2036287 | 0.88 | ALDH1A1 (0.55) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL20419240 | 0.85 | ALDH1A1 (0.57) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL29318369 | 0.85 | YTHDC1 (0.59) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL2041441 | 0.85 | YTHDC1 (0.59) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL23982425 | 0.84 | ABL1 (0.66) | ABL1RIN1 | |
| SCHEMBL9587879 | 0.84 | ADORA3 (0.46) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL23998782 | 0.84 | ABL1 (0.54) | ALDH1A1LMNAALBMAPK1ABL1 | |
| Methyl Alcohol SCHEMBL9587418 | 0.83 | ADORA3 (0.46) | ALDH1A1LMNAALBMAPK1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185437-A | 6-substituted 2',3'-dideoxypurine nucleosides; treatment for human immunodeficiency virus and heptatis b virus | BURROUGHS WELLCOME CO. (US) | 1993-02-09 | — | — | US | disclosed |
| US-5068320-A | 2-amino-6-(cyclopropylamino)purine-9-β-D-2',3'-dideoxyribofuranoside and its pharmaceutically acceptable salts | BURROUGHS WELLCOME CO. (US) | 1991-11-26 | — | — | US | disclosed |