Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TDP2 | O95551 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585920 | 0.85 | ALOX5 (0.49) | FBP1NPSR1TDP2MAPTALDH1A1 | |
| SCHEMBL9586836 | 0.81 | FBP1 (0.51) | FBP1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL9585792 | 0.80 | FBP1 (0.52) | FBP1NPSR1MAPTALDH1A1KDM4E | |
| SCHEMBL5727790 | 0.79 | FBP1 (0.69) | FBP1NPSR1MAPTTP53ALDH1A1 | |
| SCHEMBL17165899 | 0.78 | CDK2 (0.40) | FBP1NPSR1TDP2MAPTALDH1A1 | |
| SCHEMBL9585926 | 0.78 | ADORA2A (0.45) | FBP1NPSR1MAPTALDH1A1TSHR | |
| SCHEMBL9585564 | 0.78 | THRB (0.45) | FBP1CYP1A2MAPTALDH1A1TSHR | |
| SCHEMBL25292389 | 0.77 | FBP1 (0.46) | FBP1CYP1A2TDP2MAPTALDH1A1 | |
| SCHEMBL23354253 | 0.77 | FBP1 (0.45) | FBP1CYP1A2NPSR1TDP2MAPT | |
| SCHEMBL27975176 | 0.77 | ADORA2A (0.59) | FBP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204482-A | Ethylenediamine monoamide heteroaryl derivatives | HOFFMAN-LAROCHE INC. (US) | 1993-04-20 | — | — | US | disclosed |
| US-5011849-A | Monoamine oxidase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1991-04-30 | — | — | US | disclosed |