Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693060 | 0.85 | DHODH (0.31) | — | |
| SCHEMBL9588052 | 0.85 | LMNA (0.33) | GCGRCNR2 | |
| SCHEMBL9589426 | 0.84 | CNR2 (0.31) | GCGRCNR2 | |
| SCHEMBL9591291 | 0.82 | CNR2 (0.32) | GCGRCNR2 | |
| SCHEMBL9726385 | 0.80 | NPSR1 (0.36) | NOTUMKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL9726392 | 0.79 | GCGR (0.32) | GCGR | |
| SCHEMBL9726396 | 0.78 | GCGR (0.32) | GCGR | |
| SCHEMBL8693608 | 0.78 | GCGR (0.34) | GCGR | |
| SCHEMBL6732316 | 0.78 | GCGR (0.32) | GCGR | |
| SCHEMBL27674651 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196045-A | Substituted pyridine herbicides | MONSANTO COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| US-5019153-A | Substituted pyridine herbicides | MONSANTO COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0252055-A1 | Substituted pyridine herbicides | Monsanto Company (US) | 1988-01-07 | — | — | EP | disclosed |