Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PPME1 | Q9Y570 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29744143 | 0.84 | HTR6 (0.65) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL3260344 | 0.84 | HTR6 (0.65) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL21569523 | 0.82 | HTR6 (0.63) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL29560035 | 0.82 | HTR6 (0.63) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL29558135 | 0.82 | HTR6 (1.00) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL429849 | 0.82 | HTR6 (1.00) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL3956801 | 0.81 | HTR6 (0.59) | HTR6HTTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28794299 | 0.80 | HTR6 (0.96) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL9587047 | 0.80 | HTR6 (0.75) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL1673252 | 0.80 | HTR6 (0.75) | HTR6HTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013079-A1 | ANTIFOLATE QUINAZOLINES | AGOURON PHARMACEUTICALS, INC. (US) | 1993-07-08 | — | — | WO | disclosed |