Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959319 | 0.88 | MRGPRX4 (0.61) | MRGPRX4TTRPTGER1MAPTPLA2G1B | |
| SCHEMBL959981 | 0.86 | MAPT (0.48) | MRGPRX4SCN9AMAPTLMNAGPR52 | |
| SCHEMBL961250 | 0.84 | GPR52 (0.56) | MRGPRX4SCN9AFFAR4GPR52POLB | |
| SCHEMBL959429 | 0.83 | MRGPRX4 (0.49) | MRGPRX4SCN9APTGER1FFAR4ALDH1A1 | |
| SCHEMBL957915 | 0.83 | MRGPRX4 (0.50) | MRGPRX4SCN9ATTRPTGER1MAPT | |
| SCHEMBL959343 | 0.81 | MRGPRX4 (0.53) | MRGPRX4TTRPTGER1MAPTPLA2G1B | |
| SCHEMBL959528 | 0.81 | GPR52 (0.45) | MRGPRX4SCN9AGPR52ALDH1A1 | |
| SCHEMBL958072 | 0.78 | L3MBTL1 (0.51) | MRGPRX4TTRMAPTALDH1A1GAA | |
| SCHEMBL962201 | 0.77 | MRGPRX4 (0.53) | MRGPRX4TTRPTGER1ALDH1A1POLB | |
| SCHEMBL958590 | 0.76 | MRGPRX4 (0.52) | MRGPRX4TTRPTGER1MAPTPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2253618-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | GPR4, NR3C2, NR5A2 | MRGPRX4 133/4885SCN9A 1152/4885TTR 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.