Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 3/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588841 | 0.96 | TDP1 (0.40) | LMNAKDM6BKDM4CTDP1L3MBTL1 | |
| SCHEMBL9587636 | 0.91 | LMNA (0.43) | LMNATRPA1 | |
| SCHEMBL9587717 | 0.83 | LMNA (0.42) | LMNAKDM6BKDM4CTDP1L3MBTL1 | |
| SCHEMBL9587851 | 0.82 | SIGMAR1 (0.37) | LMNAKDM6BKDM4CTDP1L3MBTL1 | |
| SCHEMBL9588224 | 0.82 | TDP1 (0.41) | LMNAKDM6BKDM4CTDP1L3MBTL1 | |
| SCHEMBL9588074 | 0.81 | HTR2C (0.46) | LMNASIGMAR1 | |
| SCHEMBL9587135 | 0.80 | SIGMAR1 (0.39) | SIGMAR1 | |
| SCHEMBL9586876 | 0.78 | TDP1 (0.43) | LMNAKDM6BKDM4CTDP1L3MBTL1 | |
| SCHEMBL9588733 | 0.76 | SLC6A2 (0.49) | SIGMAR1 | |
| SCHEMBL9586748 | 0.73 | LMNA (0.47) | LMNATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | claimed |
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0383950-A1 | PYRIDINE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |