Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 8/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1129788 | 0.76 | LMNA (0.63) | LMNAGAAKMT2AALDH1A1LDHA | |
| SCHEMBL9264609 | 0.74 | LMNA (0.56) | LMNAGAAKMT2AALDH1A1LDHA | |
| SCHEMBL92986 | 0.73 | LMNA (0.59) | LMNAGAAKMT2AALDH1A1MAPT | |
| SCHEMBL2466435 | 0.72 | LMNA (0.56) | LMNAGAAKMT2AALDH1A1MAPT | |
| SCHEMBL31447811 | 0.71 | LMNA (0.60) | LMNAGAAKMT2AALDH1A1MAPT | |
| SCHEMBL21261241 | 0.71 | LMNA (0.56) | LMNAGAAKMT2AALDH1A1GLA | |
| SCHEMBL3671560 | 0.71 | ALDH1A1 (0.65) | LMNAGAAKMT2AALDH1A1GLA | |
| SCHEMBL81547 | 0.70 | LMNA (1.00) | LMNAGAAKMT2AALDH1A1MAPT | |
| SCHEMBL19342768 | 0.69 | ALDH1A1 (0.52) | LMNAGAAKMT2AALDH1A1GLA | |
| SCHEMBL12130834 | 0.69 | ALDH1A1 (0.53) | LMNAGAAKMT2AALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254595-A | Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them | ELF SANOFI (FR) | 1993-10-19 | — | — | US | disclosed |