Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9168285 | 0.84 | LMNA (0.73) | LMNAGAAKMT2AALDH1A1POLB | |
| Deferiprone SCHEMBL10563426 | 0.83 | LMNA (0.69) | LMNAGAAKMT2AALDH1A1POLB | |
| SCHEMBL16921602 | 0.81 | LMNA (0.68) | LMNAGAAKMT2AALDH1A1POLB | |
| SCHEMBL990135 | 0.81 | LMNA (0.68) | LMNAGAAKMT2AALDH1A1POLB | |
| SCHEMBL12397421 | 0.81 | LMNA (0.68) | LMNAGAAKMT2AALDH1A1POLB | |
| SCHEMBL12032476 | 0.81 | LMNA (0.68) | LMNAGAAKMT2AALDH1A1MAOB | |
| SCHEMBL12051090 | 0.81 | LMNA (0.68) | LMNAGAAKMT2AALDH1A1MAOB | |
| SCHEMBL8106278 | 0.80 | LMNA (0.65) | LMNAGAAKMT2AALDH1A1MAOB | |
| SCHEMBL6994111 | 0.80 | LMNA (0.67) | LMNAGAAKMT2AALDH1A1POLB | |
| SCHEMBL12032412 | 0.80 | LMNA (0.66) | LMNAGAAKMT2AALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 447 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119505251-A | Mitochondrial targeting iron chelating nano platform based on PAMAM and preparation method and application thereof | 重庆医科大学附属口腔医院 | 2025-02-25 | — | — | CN | claimed |
| CN-110305091-B | Preparation method of Barosavir intermediate compound | 江苏理工学院 | 2021-05-18 | — | — | CN | claimed |
| CN-110305091-A | A kind of preparation method of Ba Luoshawei midbody compound | 江苏理工学院 | 2019-10-08 | — | — | CN | claimed |
| US-20100310460-A1 | COMPOSITIONS AND METHODS FOR CHELATION THERAPY | LIU GANG | 2010-12-09 | — | — | US | claimed |
| US-20060030619-A1 | Compositions and methods for chelation therapy | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2006-02-09 | — | — | US | claimed |
| EP-3768672-B1 | 3-(HYDROXY)-PYRIDIN-4(1H)-ONE COMPOUNDS AND METHODS OF USING THE SAME | GEORGIA TECH RES INST (US) | 2026-04-29 | — | — | EP | disclosed |
| CN-121819916-A | Preparation method of catalyst and intermediate for synthesizing Marbalol Sha Wei intermediate | 安徽峆一药业股份有限公司 | 2026-04-10 | — | — | CN | disclosed |
| US-20260053929-A1 | METAL CHELATING COMPOSITIONS AND METHODS FOR CONTROLLING THE GROWTH OR ACTIVITIES OF A LIVING CELL OR ORGANISM | CHELATION PARTNERS INCORPORATED (CA) | 2026-02-26 | — | — | US | disclosed |
| US-12521382-B2 | 3-(hydroxy)-pyridin-4(1H)-one compounds and methods of making and using the same | GEORGIA TECH RESEARCH CORPORATION (US) | 2026-01-13 | — | — | US | disclosed |
| US-20250268880-A1 | 3-(Hydroxy)-Pyridin-4(1H)-One Compounds and Methods of Making and Using the Same | GEORGIA TECH RESEARCH CORPORATION | 2025-08-28 | — | — | US | disclosed |
| US-12324803-B2 | 3-(hydroxy)-pyridin-4(1H)-one compounds and methods of making and using the same | GEORGIA TECH RESEARCH CORPORATION (US) | 2025-06-10 | — | — | US | disclosed |
| CN-116478130-B | N-hydroxyquinoline carboxamide compounds and uses thereof | 深圳默元生物科技有限公司 | 2025-05-30 | — | — | CN | disclosed |
| EP-0094149-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING A COMPLEX OF IRON WITH N-SUBSTITUTED 3-HYDROXYPYRID-2-ONE OR -4-ONE DERIVATIVES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-09-10 | — | — | EP | disclosed |
| US-4585780-A | CHELATION OF HEAVY METALS IN BLOOD | NATIONAL RESEARCH DEVELOPMENT CORP. (GB) | 1986-04-29 | — | — | US | disclosed |
| US-4550101-A | Iron complexes of hydroxy pyridones useful for treating iron deficiency anemia | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-10-29 | — | — | US | disclosed |
| EP-0138421-A2 | Hydroxypyridone derivatives and pharmaceutical compositions containing them | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-04-24 | — | — | EP | disclosed |
| EP-0120669-A2 | Hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |
| EP-0120670-A1 | Iron III complexes of hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |
| EP-0094149-A2 | Pharmaceutical compositions containing a complex of iron with N-substituted 3-hydroxypyrid-2-one or -4-one derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-11-16 | — | — | EP | disclosed |
| EP-0093498-A2 | Pharmaceutical compositions containing N-substituted-3-hydroxypyrid-2-one or -4-one derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310460-A1 | COMPOSITIONS AND METHODS FOR CHELATION THERAPY | SOST, SOD3, HIF1AN | LMNA 1889/4885GAA 399/4885KMT2A 1252/4885 |
| US-20250268880-A1 | 3-(Hydroxy)-Pyridin-4(1H)-One Compounds and Methods of Making and Using the Same | KDM1B, KDM3A, KDM1A | LMNA 1791/4885GAA 3242/4885KMT2A 26/4885 |
| US-20060030619-A1 | Compositions and methods for chelation therapy | SOST, SOD3, HIF1AN | LMNA 1889/4885GAA 399/4885KMT2A 1252/4885 |
| US-12324803-B2 | 3-(hydroxy)-pyridin-4(1H)-one compounds and methods of making and using the same | KDM1B, KDM3A, KDM1A | LMNA 1791/4885GAA 3242/4885KMT2A 26/4885 |
| US-20260053929-A1 | METAL CHELATING COMPOSITIONS AND METHODS FOR CONTROLLING THE GROWTH OR ACTIVITIES OF A LIVING CELL OR ORGANISM | HAMP, SLC40A1, TFRC | LMNA 1956/4885GAA 433/4885KMT2A 3081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.