SCHEMBL9588997

SCHEMBL9588997

O=C1/C(=N\O)C(=O)N(Cc2ccccc2)c2ccccc21

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.69
ALDH3A1 P30838 8/20 0.69
CES1 P23141 4/20 0.69
ALDH2 P05091 4/20 0.69
CHRM1 P11229 2/20 0.69
MAPT P10636 3/20 0.59
TSHR P16473 2/20 0.59
HSD17B10 Q99714 2/20 0.59
LRRK2 Q5S007 1/20 0.59
PKM P14618 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
ACHE P22303 2/20 0.57
BCHE P06276 2/20 0.56
CES2 O00748 1/20 0.56
CA2 P00918 2/20 0.55
CA12 O43570 1/20 0.55
CA9 Q16790 1/20 0.55
CHRM5 P08912 2/20 0.55
CHRM3 P20309 1/20 0.55
CA1 P00915 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9589000 1.00 ALDH1A1 (0.69) ALDH1A1ALDH3A1CES1ALDH2CHRM1
SCHEMBL7611054 0.91 ALDH1A1 (0.66) ALDH1A1ALDH3A1CES1ALDH2CHRM1
SCHEMBL7611051 0.91 ALDH1A1 (0.66) ALDH1A1ALDH3A1CES1ALDH2CHRM1
SCHEMBL29506660 0.82 ALDH1A1 (1.00) ALDH1A1ALDH3A1CES1ALDH2CHRM1
SCHEMBL2087729 0.82 ALDH1A1 (1.00) ALDH1A1ALDH3A1CES1ALDH2CHRM1
SCHEMBL13627881 0.81 CES1 (0.67) ALDH1A1ALDH3A1CES1ALDH2CHRM1
Ammonia Solution, Strong SCHEMBL27858936 0.81 ALDH1A1 (0.96) ALDH1A1ALDH3A1CES1ALDH2CHRM1
SCHEMBL13627885 0.81 ALDH1A1 (0.54) ALDH1A1ALDH3A1CES1ALDH2CHRM1
SCHEMBL13627880 0.80 ALDH1A1 (0.70) ALDH1A1ALDH3A1CES1ALDH2CHRM1
SCHEMBL13627894 0.80 LMNA (0.59) ALDH1A1ALDH3A1CES1ALDH2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5190956-A Certain N-substituted 3-oximino-2,4-dioxoquinolin-2,4-(1H)diones useful for treating viral infections SCHERING CORPORATION (US) 1993-03-02 US disclosed
US-5179107-A Herpes SCHERING CORPORATION (US) 1993-01-12 US disclosed