Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | PGK2 | P07205 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681270 | 0.81 | CHEK1 (0.45) | PARP1CHEK1TDP1NPSR1RHEB | |
| SCHEMBL9588283 | 0.78 | GRIN2D (0.48) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL9587955 | 0.77 | GRIN2D (0.47) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL9589055 | 0.77 | GRIN2D (0.49) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL9588065 | 0.76 | GRIN2B (0.43) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL9533100 | 0.73 | GRIN1 (0.55) | GRIN1GRIN2BCHEK1TDP1NPSR1 | |
| SCHEMBL11498419 | 0.72 | LIPG (0.40) | CHEK1 | |
| SCHEMBL5744116 | 0.71 | EGLN1 (0.42) | GRIN1GRIN2BPARP1CHEK1TDP1 | |
| SCHEMBL14300571 | 0.71 | TDP1 (0.40) | GRIN1GRIN2BPARP1CHEK1TDP1 | |
| SCHEMBL3938941 | 0.71 | CHEK1 (0.57) | GRIN1GRIN2BPARP1CHEK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216003-A | Antihypoxic, antiischemic agents | G. D. SEARLE & CO. (US) | 1993-06-01 | — | — | US | disclosed |