Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.37 |
| ▸ | CD74 | P04233 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266360 | 0.82 | THRB (0.40) | MIFCD74KMT2AMEN1ALDH1A1 | |
| SCHEMBL9591350 | 0.79 | TMEM97 (0.53) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL17813554 | 0.77 | NOS1 (0.36) | MIFCD74KMT2APOLBMEN1 | |
| SCHEMBL9589803 | 0.74 | KDM4E (0.58) | MIFKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL2542484 | 0.72 | POLB (0.50) | MIFCD74KMT2APOLBMEN1 | |
| SCHEMBL16141179 | 0.71 | ALDH1A1 (0.64) | MIFCD74KMT2APOLBMEN1 | |
| SCHEMBL12241213 | 0.69 | TNIK (0.40) | MIFCD74KMT2AALDH1A1KDM4E | |
| SCHEMBL2544405 | 0.69 | POLB (0.45) | MIFCD74KMT2APOLBMEN1 | |
| SCHEMBL2542519 | 0.68 | POLB (0.43) | MIFCD74KMT2APOLBMEN1 | |
| SCHEMBL2544400 | 0.68 | TNIK (0.55) | MIFCD74KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190960-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1993-03-02 | — | — | US | disclosed |
| US-5155116-A | Analgesics devoid of antiinflammatory activity | ADIR ET COMPAGNIE (FR) | 1992-10-13 | — | — | US | disclosed |