SCHEMBL9590881

SCHEMBL9590881

[N-]=[N+]=C1CN([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)C(=O)NC1=O

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TYMS P04818 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7148871 0.83 TK1 (0.41) —
SCHEMBL7148864 0.83 TK1 (0.41) —
SCHEMBL31685506 0.77 TYMS (0.48) TYMS
SCHEMBL10710276 0.75 P2RY2 (0.45) —
SCHEMBL31678749 0.75 TYMS (0.48) TYMS
Thymidine Monophosphate SCHEMBL17075779 0.69 POLB (0.74) TYMS
SCHEMBL30866446 0.68 TYMS (0.48) TYMS
SCHEMBL20472322 0.67 TYMS (0.50) TYMS
SCHEMBL15189813 0.67 UMPS (0.55) TYMS
SCHEMBL31685198 0.67 TYMS (0.48) TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0218701-B1 5-AZIDO DEOXYURIDINE COMPOUNDS AND METHOD OF SYNTHESIS OF THE SAME THE UNIVERSITY OF WYOMING (US) 1993-08-04 — — EP claimed
EP-0218701-A4 5-AZIDO DEOXYURIDINE COMPOUNDS AND METHOD OF SYNTHESIS OF THE SAME. UNIV WYOMING (US) 1988-09-28 — — EP claimed
US-4672111-A 5-azido-deoxyuridine compounds and method of synthesis of the same UNIVERSITY OF WYOMING (US) 1987-06-09 — — US claimed
EP-0218701-A1 5-AZIDO DEOXYURIDINE COMPOUNDS AND METHOD OF SYNTHESIS OF THE SAME. UNIV WYOMING (US) 1987-04-22 — — EP claimed
WO-1986006253-A1 5-AZIDO DEOXYURIDINE COMPOUNDS AND METHOD OF SYNTHESIS OF THE SAME THE UNIVERSITY OF WYOMING (US) 1986-11-06 — — WO claimed
EP-0218701-B1 5-AZIDO DEOXYURIDINE COMPOUNDS AND METHOD OF SYNTHESIS OF THE SAME THE UNIVERSITY OF WYOMING (US) 1993-08-04 — — EP disclosed
EP-0218701-A4 5-AZIDO DEOXYURIDINE COMPOUNDS AND METHOD OF SYNTHESIS OF THE SAME. UNIV WYOMING (US) 1988-09-28 — — EP disclosed
US-4672111-A 5-azido-deoxyuridine compounds and method of synthesis of the same UNIVERSITY OF WYOMING (US) 1987-06-09 — — US disclosed
EP-0218701-A1 5-AZIDO DEOXYURIDINE COMPOUNDS AND METHOD OF SYNTHESIS OF THE SAME. UNIV WYOMING (US) 1987-04-22 — — EP disclosed
WO-1986006253-A1 5-AZIDO DEOXYURIDINE COMPOUNDS AND METHOD OF SYNTHESIS OF THE SAME THE UNIVERSITY OF WYOMING (US) 1986-11-06 — — WO disclosed
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