Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 11/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593119 | 0.92 | DDR1 (0.36) | DDR1CDK4CCND1GABRB3GABRA2 | |
| SCHEMBL9723046 | 0.88 | GABRB3 (0.39) | DDR1CDK4CCND1GABRB3GABRA2 | |
| SCHEMBL9592278 | 0.87 | KDM5B (0.32) | DDR1 | |
| SCHEMBL9591741 | 0.80 | — | — | |
| SCHEMBL9582428 | 0.80 | GAA (0.40) | DDR1CDK4CCND1GABRB3GABRA2 | |
| SCHEMBL9723126 | 0.79 | TDP1 (0.44) | CDK4CCND1 | |
| SCHEMBL9594110 | 0.78 | L3MBTL1 (0.35) | DDR1GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9592805 | 0.75 | GABRA2 (0.33) | DDR1GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9593317 | 0.73 | GABRA2 (0.34) | DDR1GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9723060 | 0.73 | PDE2A (0.39) | DDR1GABRB3GABRA2GABRB2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553119-A1 | HETEROCYCLIC COMPOUNDS | ZENECA LIMITED (GB) | 1993-08-04 | — | — | EP | disclosed |
| US-5187176-A | 1-PHENYL SUBSTITUTED PYRIMIDONE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-16 | — | — | US | disclosed |
| WO-1992006964-A1 | HETEROCYCLIC COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-30 | — | — | WO | disclosed |