Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592705 | 0.93 | MEN1 (0.46) | SLC2A1EGFRERBB2KDM1AMEN1 | |
| SCHEMBL9594919 | 0.93 | MEN1 (0.46) | SLC2A1EGFRERBB2KDM1AMEN1 | |
| SCHEMBL9594500 | 0.93 | KDM1A (0.49) | SLC2A1EGFRERBB2KDM1AMAP2K1 | |
| SCHEMBL9593647 | 0.92 | KDM1A (0.50) | SLC2A1EGFRERBB2KDM1AMAP2K1 | |
| SCHEMBL9595308 | 0.89 | KDM1A (0.56) | KDM1AACHE | |
| SCHEMBL9594446 | 0.88 | HDAC1 (0.54) | EGFRKDM1AMAP2K1MEN1KMT2A | |
| SCHEMBL9593806 | 0.88 | KDM1A (0.54) | SLC2A1EGFRERBB2KDM1AMAP2K1 | |
| SCHEMBL9594474 | 0.88 | KDM1A (0.51) | SLC2A1EGFRERBB2KDM1AMAP2K1 | |
| SCHEMBL9594966 | 0.88 | KDM1A (0.54) | SLC2A1EGFRERBB2KDM1AMAP2K1 | |
| SCHEMBL9594080 | 0.88 | TOP2A (0.58) | EGFRERBB2KDM1APDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | claimed |
| US-5229395-A | Potential anticancer agents derived from acridine | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1993-07-20 | — | — | US | disclosed |
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | disclosed |