Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593806 | 0.94 | KDM1A (0.54) | KDM1APDPK1MAP2K1EGFRKDR | |
| SCHEMBL9594966 | 0.94 | KDM1A (0.54) | KDM1APDPK1MAP2K1EGFRKDR | |
| SCHEMBL9594474 | 0.94 | KDM1A (0.51) | KDM1APDPK1MAP2K1EGFRKDR | |
| SCHEMBL9594446 | 0.92 | HDAC1 (0.54) | KDM1AMAP2K1EGFRCSF1RTP53 | |
| SCHEMBL9592698 | 0.92 | KDM1A (0.53) | KDM1APDPK1MAP2K1EGFRCSF1R | |
| SCHEMBL9594824 | 0.92 | SLC2A1 (0.48) | KDM1APDPK1MAP2K1EGFRSLC2A1 | |
| SCHEMBL9594500 | 0.92 | KDM1A (0.49) | KDM1APDPK1MAP2K1EGFRKDR | |
| SCHEMBL9594205 | 0.89 | KDM1A (0.48) | KDM1APDPK1MAP2K1EGFRKDR | |
| SCHEMBL9595558 | 0.89 | KDM1A (0.48) | KDM1APDPK1MAP2K1EGFRKDR | |
| SCHEMBL9595683 | 0.85 | TOP2A (0.64) | PDPK1EGFRKDRCSF1RTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | claimed |
| US-5229395-A | Potential anticancer agents derived from acridine | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1993-07-20 | — | — | US | disclosed |
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | disclosed |