Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595308 | 0.95 | KDM1A (0.56) | KDM1AACHETOP2ATOP2B | |
| SCHEMBL9594322 | 0.95 | KDM1A (0.53) | KDM1AACHETOP2ATOP2B | |
| SCHEMBL9595398 | 0.91 | KDM1A (0.51) | KDM1AACHETOP2ATOP2B | |
| SCHEMBL9594083 | 0.91 | KDM1A (0.67) | KDM1ATOP2ATOP2B | |
| SCHEMBL9594310 | 0.91 | KDM1A (0.51) | KDM1AACHETOP2ATOP2B | |
| SCHEMBL9594932 | 0.91 | KDM1A (0.65) | KDM1AACHETOP2ATOP2B | |
| SCHEMBL9593226 | 0.90 | HDAC1 (0.57) | KDM1A | |
| SCHEMBL9595076 | 0.90 | HDAC1 (0.55) | KDM1A | |
| SCHEMBL9594500 | 0.87 | KDM1A (0.49) | KDM1AACHE | |
| SCHEMBL9594824 | 0.87 | SLC2A1 (0.48) | KDM1AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225409-A | Serotoninergic disorders; anxiolytic agents; schizophrenia | ADIR ET COMPAGNIE (FR) | 1993-07-06 | — | — | US | disclosed |