SCHEMBL9595102

SCHEMBL9595102

CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NCC1CCCO1

nearest known ligand 0.78

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.78
CTSK P43235 12/20 0.61
CTSS P25774 7/20 0.61
CTSL P07711 6/20 0.61
CTSB P07858 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7163169 0.89 CTSK (0.67) CYP1A2CTSKCTSSCTSLCTSB
SCHEMBL12115243 0.84 CYP1A2 (0.68) CYP1A2CTSKCTSSCTSLCTSB
SCHEMBL4342556 0.84 CYP1A2 (0.68) CYP1A2CTSKCTSSCTSLCTSB
SCHEMBL7379607 0.82 CTSK (0.58) CYP1A2CTSKCTSSCTSLCTSB
SCHEMBL14451638 0.80 CTSK (0.60) CTSKCTSSCTSLCTSB
SCHEMBL7515987 0.79 CTSK (0.61) CTSKCTSSCTSLCTSB
SCHEMBL7514927 0.78 CTSK (0.77) CTSKCTSSCTSLCTSB
SCHEMBL9115066 0.78 CAPN1 (0.80) CTSKCTSSCTSLCTSB
SCHEMBL7402633 0.78 CTSK (0.76) CTSKCTSSCTSLCTSB
SCHEMBL7411658 0.78 CTSK (0.76) CTSKCTSSCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993015047-A1 AMINO ACID DERIVATIVES AS PAF ANTAGONISTS BRITISH BIO-TECHNOLOGY LIMITED (GB) 1993-08-05 WO claimed
WO-1993015047-A1 AMINO ACID DERIVATIVES AS PAF ANTAGONISTS BRITISH BIO-TECHNOLOGY LIMITED (GB) 1993-08-05 WO disclosed