SCHEMBL9595405

SCHEMBL9595405

CC(C)NCCCCCC(=O)N1c2ccc(Cl)cc2NC(=O)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 12/20 0.47
DRD2 P14416 2/20 0.44
CHRM1 P11229 1/20 0.42
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9594700 0.89 CHRM2 (0.56) CHRM2CHRM1
SCHEMBL9595164 0.88 CHRM2 (0.54) CHRM2DRD2CHRM1
Hydrochloric Acid SCHEMBL9596500 0.87 CHRM2 (0.54) CHRM2DRD2CHRM1
SCHEMBL9595120 0.84 DRD2 (0.46) CHRM2DRD2CHRM1RAB9A
SCHEMBL9595138 0.84 DRD2 (0.46) CHRM2DRD2CHRM1RAB9A
SCHEMBL9595385 0.84 CHRM2 (0.43) CHRM2DRD2CHRM1
SCHEMBL9594444 0.83 DRD2 (0.45) CHRM2DRD2CHRM1RAB9A
SCHEMBL9594641 0.82 CHRM2 (0.55) CHRM2DRD2CHRM1
SCHEMBL9593883 0.82 CHRM2 (0.55) CHRM2DRD2CHRM1
SCHEMBL9593547 0.81 CHRM2 (0.55) CHRM2DRD2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5264432-A Antiarrhythmia and anticholinergic agents ARZNEIMITTELWERK DRESDEN G.M.B.H (DD) 1993-11-23 US claimed