Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929913 | 0.87 | LMNA (0.37) | LMNACYP2C9HTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL14880059 | 0.85 | LMNA (0.36) | LMNACYP2C9 | |
| SCHEMBL13210519 | 0.83 | LMNA (0.34) | LMNACYP2C9KMT2A | |
| Pyrrolidine SCHEMBL21806662 | 0.81 | MAPK1 (0.43) | LMNACYP2C9ALDH1A1MAPK1 | |
| SCHEMBL278331 | 0.80 | — | — | |
| SCHEMBL13676319 | 0.80 | — | — | |
| Piperidine SCHEMBL23701649 | 0.79 | ALDH1A1 (0.43) | LMNACYP2C9ALDH1A1MAPK1 | |
| SCHEMBL5244079 | 0.79 | CXCR4 (0.43) | LMNACYP2C9ALDH1A1TDP1MAPK1 | |
| SCHEMBL2292002 | 0.78 | HTR6 (0.42) | LMNACYP2C9MAPK1 | |
| SCHEMBL31208679 | 0.74 | HTR6 (0.39) | LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179090-A | Antiischemic agents; treatment of asthma, bronchitis, heart diseases | DR. KARL THOMAE GMBH (DE) | 1993-01-12 | — | — | US | disclosed |