Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CTH | P32929 | 1/20 | 0.39 |
| ▸ | CBS | P35520 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168709 | 0.97 | — | — | |
| SCHEMBL27845788 | 0.94 | TSHR (0.39) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL28279642 | 0.94 | TSHR (0.39) | TSHRCTHCBSTHPOTHRB | |
| Ammonia Solution, Strong SCHEMBL11317665 | 0.94 | TSHR (0.39) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL11280732 | 0.94 | TSHR (0.39) | TSHRCTHCBSTHPOTHRB | |
| Succinic Acid SCHEMBL11249487 | 0.87 | LMNA (0.43) | TSHRCTHCBSTHPOTHRB | |
| Monoethanolamine SCHEMBL5030530 | 0.84 | TSHR (0.37) | TSHRCTHCBSTHPOTHRB | |
| Monoethanolamine SCHEMBL27678397 | 0.84 | TSHR (0.37) | TSHRCTHCBSTHPOTHRB | |
| Octane SCHEMBL28758977 | 0.82 | PAM (0.50) | TSHRALDH1A1CA2ALOX15TDP1 | |
| Triphosphate SCHEMBL10788307 | 0.77 | MVD (0.39) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270334-A | 4-methoxy-5-methyl-pyran-3-ol natural products and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1993-12-14 | — | — | US | disclosed |