Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 8/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 7/20 | 0.58 |
| ▸ | AGT | P01019 | 2/20 | 0.48 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595666 | 1.00 | AGTR2 (0.58) | AGTR2AGTR1AGTGP6 | |
| SCHEMBL10429955 | 0.94 | AGTR2 (0.51) | AGTR2AGTR1AGTGP6 | |
| SCHEMBL10429953 | 0.94 | AGTR2 (0.51) | AGTR2AGTR1AGTGP6 | |
| SCHEMBL9595557 | 0.90 | AGTR1 (0.56) | AGTR2AGTR1AGT | |
| SCHEMBL9595549 | 0.90 | AGTR1 (0.56) | AGTR2AGTR1AGT | |
| SCHEMBL9594411 | 0.89 | AGTR2 (0.55) | AGTR2AGTR1AGT | |
| SCHEMBL9594545 | 0.89 | AGTR2 (0.65) | AGTR2AGTR1AGTGP6 | |
| SCHEMBL9030644 | 0.88 | AGTR2 (0.67) | AGTR2AGTR1AGTGP6 | |
| SCHEMBL9090 | 0.87 | AGTR2 (0.65) | AGTR2AGTR1AGTGP6 | |
| SCHEMBL9029527 | 0.86 | AGTR2 (0.64) | AGTR2AGTR1AGTGP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254546-A | Hypotensive agent | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0479892-A1 | FUSED-RING ARYL SUBSTITUTED IMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-15 | — | — | EP | disclosed |
| WO-1991000281-A2 | FUSED-RING ARYL SUBSTITUTED IMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-10 | — | — | WO | disclosed |