Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10610746 | 0.88 | ALDH1A1 (0.44) | EPHX2CCR5CHRNA7POLB | |
| SCHEMBL4186680 | 0.85 | POLB (0.41) | EPHX2ACACBCCR5KDM4ECHRNA7 | |
| SCHEMBL9450741 | 0.85 | EPHX2 (0.49) | EPHX2ACACB | |
| SCHEMBL10609014 | 0.84 | CCR5 (0.48) | EPHX2CCR5POLB | |
| SCHEMBL9597256 | 0.83 | GRIN1 (0.47) | EPHX2 | |
| SCHEMBL9597771 | 0.83 | PARP10 (0.42) | EPHX2ACACBCCR5CHRNA7POLB | |
| SCHEMBL15301072 | 0.83 | ALDH1A1 (0.50) | EPHX2ACACBCCR5 | |
| SCHEMBL9477316 | 0.83 | SCD (0.51) | EPHX2RIPK1SCD | |
| SCHEMBL9596749 | 0.81 | SLC6A2 (0.51) | EPHX2KDM4ESMN1; SMN2POLBRIPK1 | |
| SCHEMBL27037359 | 0.81 | NAMPT (0.46) | EPHX2ACACBCCR5KDM4ECHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183902-A | Muscle relaxants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-02-02 | — | — | US | disclosed |
| US-5151418-A | Muscle relaxants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-09-29 | — | — | US | disclosed |
| US-5068231-A | Ureas and thioureas for relaxing muscles | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| US-4956359-A | CARBOXAMIDES OR THIOCARBOXAMIDES OF ARYL OXY OR THIO AZETIDINES | A. H. ROBINS COMPANY, INC. (US) | 1990-09-11 | — | — | US | disclosed |