Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.62 |
| ▸ | NAE1 | Q13564 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.62 |
| ▸ | PPARG | P37231 | 2/20 | 0.62 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MLNR | O43193 | 1/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477228 | 0.93 | AGTR2 (0.71) | AGTR1AGTR2NAE1CYP3A4ADORA3 | |
| SCHEMBL9007006 | 0.90 | AGTR1 (0.65) | AGTR1AGTR2NAE1CYP3A4ADORA3 | |
| SCHEMBL9596166 | 0.86 | AGTR1 (0.59) | AGTR1AGTR2NAE1CYP3A4ADORA3 | |
| SCHEMBL9594215 | 0.85 | AGTR1 (0.68) | AGTR1AGTR2NAE1CYP3A4ADORA3 | |
| SCHEMBL9594207 | 0.84 | AGTR1 (0.54) | AGTR1AGTR2CYP3A4ADORA3ADRA2B | |
| SCHEMBL14522914 | 0.84 | NAE1 (0.75) | AGTR1AGTR2NAE1CYP3A4ADORA3 | |
| SCHEMBL30007325 | 0.84 | NAE1 (0.75) | AGTR1AGTR2NAE1CYP3A4ADORA3 | |
| SCHEMBL1653579 | 0.84 | AGTR2 (0.57) | AGTR1AGTR2NAE1CYP3A4ADORA3 | |
| SCHEMBL6850571 | 0.83 | NAE1 (0.74) | AGTR1AGTR2NAE1CYP3A4ADORA3 | |
| SCHEMBL15478919 | 0.83 | NAE1 (0.74) | AGTR1AGTR2NAE1CYP3A4ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018030-A1 | BENZIMIDAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-16 | — | — | WO | disclosed |