Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | F13A1 | P00488 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2922043 | 0.91 | LMNA (0.46) | TSHRLMNANFKB1PMP22F13A1 | |
| SCHEMBL8812768 | 0.84 | TSHR (0.67) | TSHRLMNANFKB1PMP22F13A1 | |
| SCHEMBL30427829 | 0.82 | F13A1 (0.48) | TSHRLMNANFKB1PMP22F13A1 | |
| SCHEMBL2345633 | 0.81 | FFAR1 (0.43) | LMNAFFAR1FFAR4 | |
| SCHEMBL29009797 | 0.79 | HDAC3 (0.39) | TSHRLMNANFKB1PMP22F13A1 | |
| SCHEMBL29009970 | 0.79 | HDAC3 (0.39) | TSHRLMNANFKB1PMP22F13A1 | |
| SCHEMBL30831169 | 0.78 | FAAH (0.54) | MEN1KMT2AHSD17B10 | |
| Sebacic Acid SCHEMBL26976880 | 0.75 | TSHR (0.92) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL29009918 | 0.75 | HDAC3 (0.44) | TSHRLMNAF13A1FFAR1FFAR4 | |
| SCHEMBL22160483 | 0.75 | ALDH1A1 (0.41) | TSHRLMNANFKB1PMP22SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015047-A1 | AMINO ACID DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-05 | — | — | WO | disclosed |