Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.68 |
| ▸ | DRD3 | P35462 | 3/20 | 0.68 |
| ▸ | HTR1A | P08908 | 8/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | HTR7 | P34969 | 6/20 | 0.67 |
| ▸ | DRD5 | P21918 | 1/20 | 0.63 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9595986 | 0.99 | DRD2 (0.67) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL8419556 | 0.87 | HTR2A (0.67) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL9376347 | 0.83 | DRD2 (0.71) | DRD2DRD3HTR1AHTR7DRD5 | |
| Hydrochloric Acid SCHEMBL9380070 | 0.82 | DRD2 (0.69) | DRD2DRD3HTR1AHTR7DRD5 | |
| Hydrochloric Acid SCHEMBL9383611 | 0.80 | HTR2A (0.78) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL22048363 | 0.80 | HTR1A (1.00) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL14761916 | 0.80 | DRD2 (0.77) | DRD2DRD3HTR1AHTR7DRD5 | |
| SCHEMBL6185115 | 0.78 | HTR2A (0.65) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL8831407 | 0.78 | HTR2A (0.64) | DRD2HTR1AHTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9376254 | 0.78 | HTR1A (0.65) | DRD2DRD3HTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016073-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES, AND THEIR USE AS ANTIPSYCHOTICS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-08-19 | — | — | WO | claimed |
| WO-1993016073-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES, AND THEIR USE AS ANTIPSYCHOTICS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-08-19 | — | — | WO | disclosed |