Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.71 |
| ▸ | DRD3 | P35462 | 4/20 | 0.71 |
| ▸ | HTR7 | P34969 | 12/20 | 0.69 |
| ▸ | HTR1A | P08908 | 9/20 | 0.69 |
| ▸ | DRD5 | P21918 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9380070 | 0.99 | DRD2 (0.69) | DRD2DRD3HTR7HTR1ADRD5 | |
| SCHEMBL9596303 | 0.83 | DRD2 (0.68) | DRD2DRD3HTR7HTR1ADRD5 | |
| Hydrochloric Acid SCHEMBL9595986 | 0.82 | DRD2 (0.67) | DRD2DRD3HTR7HTR1ADRD5 | |
| SCHEMBL14761916 | 0.82 | DRD2 (0.77) | DRD2DRD3HTR7HTR1ADRD5 | |
| SCHEMBL14761316 | 0.79 | DRD2 (0.68) | DRD2DRD3HTR7HTR1ADRD5 | |
| SCHEMBL9375671 | 0.77 | NPC1 (0.43) | DRD2DRD3HTR7HTR1A | |
| SCHEMBL10542355 | 0.76 | HTR7 (0.98) | DRD2DRD3HTR7HTR1ADRD5 | |
| SCHEMBL22001855 | 0.76 | DRD2 (0.86) | DRD2DRD3HTR7HTR1ADRD5 | |
| SCHEMBL14761592 | 0.75 | DRD2 (0.65) | DRD2DRD3HTR7HTR1ADRD5 | |
| SCHEMBL4430426 | 0.74 | HTR1A (0.64) | DRD2DRD3HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625978-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES, AND THEIR USE AS ANTIPSYCHOTICS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-30 | — | — | EP | claimed |