Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570028 | 0.83 | KDM4E (0.35) | KDM4EALDH1A1POLBGFER | |
| SCHEMBL19514881 | 0.78 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL2608598 | 0.73 | UHRF1 (0.37) | KDM4EALDH1A1POLBGFER | |
| SCHEMBL25282885 | 0.69 | WDR5 (0.46) | KDM4EALDH1A1GFER | |
| SCHEMBL19514974 | 0.69 | KDM4E (0.35) | KDM4EALDH1A1POLBGFER | |
| SCHEMBL16387194 | 0.69 | KDM4E (0.32) | KDM4EALDH1A1POLBGFER | |
| SCHEMBL871216 | 0.68 | ALDH1A1 (0.44) | KDM4EALDH1A1GFER | |
| SCHEMBL4769855 | 0.68 | KDM4E (0.38) | KDM4EALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL15006712 | 0.67 | UHRF1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL3843155 | 0.64 | ADRB1 (0.36) | KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |