Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.45 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5183 | 0.83 | HTR7 (0.51) | HTR7ALOX5ALDH1A1MAOB | |
| SCHEMBL29574709 | 0.83 | HTR7 (0.51) | HTR7ALOX5ALDH1A1MAOB | |
| SCHEMBL26971102 | 0.81 | NPC1 (0.61) | RAB9AHTR7NPC1ALDH1A1CYP2D6 | |
| SCHEMBL1192486 | 0.79 | MAOB (0.55) | HTR7CYP2D6CYP2C19CYP1A2MAOB | |
| SCHEMBL22127150 | 0.79 | GABRA5 (0.47) | RAB9ACNR1CNR2ALOX5TLR4 | |
| SCHEMBL25930635 | 0.79 | MAOB (0.51) | RAB9AHTR7NPC1ALDH1A1CYP2D6 | |
| SCHEMBL26971159 | 0.79 | HTR7 (0.47) | RAB9AHTR7NPC1ALDH1A1CYP2D6 | |
| SCHEMBL8726267 | 0.79 | MAOB (0.51) | RAB9AHTR7NPC1MAOB | |
| SCHEMBL9598864 | 0.78 | CNR1 (0.48) | RAB9ACNR1CNR2ALOX5NPC1 | |
| SCHEMBL8265170 | 0.78 | MAOB (0.48) | HTR7MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196422-A | Antiinflammatory agents, antiallergens | ICI PHARMA (FR) | 1993-03-23 | — | — | US | disclosed |
| US-5089513-A | Antiinflammatory agents; antiallergens; asthma; side effect reduction | ICI PHARMA (FR) | 1992-02-18 | — | — | US | disclosed |