Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29574709 | 1.00 | HTR7 (0.51) | HTR7MAOBALOX5GABRG2GABRB3 | |
| SCHEMBL2524154 | 0.88 | L3MBTL1 (0.52) | MAOBALOX5TSHRTRPV3L3MBTL1 | |
| Formic Acid Methyl Ester SCHEMBL30865550 | 0.88 | HTR7 (0.46) | HTR7MAOBALOX5GABRG2GABRB3 | |
| SCHEMBL6437530 | 0.85 | HTR7 (0.53) | HTR7MAOBALOX5GABRG2GABRB3 | |
| SCHEMBL8726267 | 0.84 | MAOB (0.51) | HTR7MAOBTSHRL3MBTL1MAPT | |
| SCHEMBL31375611 | 0.83 | MAOB (0.53) | MAOBALOX5TSHRTRPV3L3MBTL1 | |
| SCHEMBL17459263 | 0.83 | MAOB (0.53) | MAOBALOX5TSHRTRPV3L3MBTL1 | |
| SCHEMBL9598308 | 0.83 | RAB9A (0.48) | HTR7MAOBALOX5ALDH1A1 | |
| SCHEMBL4688 | 0.82 | HTR7 (0.57) | HTR7ALOX5TDP1ALDH1A1HPGD | |
| SCHEMBL30464973 | 0.82 | HTR7 (0.45) | HTR7MAPTMAPK1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121421-B1 | BIARYL DERIVATIVES AS YAP/TAZ-TEAD PROTEIN-PROTEIN INTERACTION INHIBITORS | NOVARTIS AG (CH) | 2026-03-11 | — | — | EP | disclosed |
| EP-4271674-B9 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES INC (US) | 2026-03-11 | — | — | EP | disclosed |
| US-12570642-B2 | GLP-IR modulating compounds | GILEAD SCIENCES, INC. (US) | 2026-03-10 | — | — | US | disclosed |
| US-12552767-B2 | 3-heteroaryl pyrrolidine and piperidine orexin receptor agonists | MERCK SHARP & DOHME LLC (US) | 2026-02-17 | — | — | US | disclosed |
| EP-4691554-A2 | GLP-1R MODULATING COMPOUNDS | Gilead Sciences, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-3623372-B1 | PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS | VALO HEALTH INC (US) | 2026-02-04 | — | — | EP | disclosed |
| US-12497382-B2 | GLP-1R modulating compounds | GILEAD SCIENCES, INC. (US) | 2025-12-16 | — | — | US | disclosed |
| EP-4658660-A1 | MACROCYCLIC OREXIN RECEPTOR AGONISTS AND USES THEREOF | Jazz Pharmaceuticals Ireland Limited (IE) | 2025-12-10 | — | — | EP | disclosed |
| EP-4271672-B1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES INC (US) | 2025-12-03 | — | — | EP | disclosed |
| EP-4271674-B3 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES INC (US) | 2025-12-03 | — | — | EP | disclosed |
| US-6211220-B1 | ANTITUMOR AGENTS AND ANTICARCIINOGENIC AGENTS | CELL PATHWAYS, INC. | 2001-04-03 | — | — | US | disclosed |
| US-5840654-A | COMBATING UNDESIRED PLANT GROWTH BY TREATING LOCUS WITH SPECIFIED HERBICIDE | AMERICAN CYANAMID COMPANY (US) | 1998-11-24 | — | — | US | disclosed |
| EP-0690846-B1 | HERBICIDAL HETEROCYCLIC-SUBSTITUTED PYRIDINES | SHELL INT RESEARCH (NL) | 1998-01-07 | — | — | EP | disclosed |
| CN-1122596-A | Herbicidal heterocyclic-substituted pyridines | SHELL INT RESEARCH (NL) | 1996-05-15 | — | — | CN | disclosed |
| EP-0690846-A1 | HERBICIDAL HETEROCYCLIC-SUBSTITUTED PYRIDINES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1996-01-10 | — | — | EP | disclosed |
| EP-0535980-B1 | 2-Pyridone derivatives, a process for their preparation and their use as fungicides | SUMITOMO CHEMICAL CO (JP) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994029277-A1 | AMILINO- OR PYRIDYLAMINO- CYCLOBUTENE- 1,2-DIONE DERIVATIVES AS cGMP PHOSPHODIESTERASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1994-12-22 | — | — | WO | disclosed |
| WO-1994022833-A1 | HERBICIDAL HETEROCYCLIC-SUBSTITUTED PYRIDINES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-10-13 | — | — | WO | disclosed |
| US-5322845-A | Controlling plant diseases | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0535980-A1 | 2-Pyridone derivatives, a process for their preparation and their use as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552767-B2 | 3-heteroaryl pyrrolidine and piperidine orexin receptor agonists | HCRTR2, HCRTR1, NPY1R | HTR7 44/4885MAOB 360/4885ALOX5 947/4885 |
| US-12570642-B2 | GLP-IR modulating compounds | GLP1R, GIPR, GPR119 | HTR7 281/4885MAOB 4177/4885ALOX5 4703/4885 |
| US-12497382-B2 | GLP-1R modulating compounds | GLP1R, GIPR, GPR119 | HTR7 280/4885MAOB 3970/4885ALOX5 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.