Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RHEB | Q15382 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | PKN1 | Q16512 | 5/20 | 0.52 |
| ▸ | PKN2 | Q16513 | 5/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9598691 | 0.83 | MAPT (0.68) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL9598512 | 0.81 | PRKD3 (0.43) | ALDH1A1KDM4ERHEBNPC1RAB9A | |
| SCHEMBL9599277 | 0.81 | SLC2A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL9598976 | 0.80 | FBP1 (0.53) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9678498 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL9378150 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL9379605 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL9704460 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL30433593 | 0.74 | PDE3B (0.59) | PDE3BPDE3AGSK3BMAPK1 | |
| SCHEMBL9679051 | 0.74 | PDE3B (0.57) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212186-A | Asthma, anticoagulant | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1993-05-18 | — | — | US | disclosed |
| EP-0473963-A1 | Pyrrolobenzimidazoles, imidazobenzoxazinones, and imidazoquinolones, processes for their preparation and their use as well as compositions containing these compounds | Beiersdorf-Lilly GmbH (DE) | 1992-03-11 | — | — | EP | disclosed |