Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 6/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9598271 | 0.82 | PDE4B (0.35) | KDM4CNPC1RAB9APTPN1PDE4B | |
| SCHEMBL15013651 | 0.82 | KDM4C (0.45) | KDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL7366055 | 0.81 | DHFR (0.40) | KDM4CNPC1RAB9APTPN1PDE4B | |
| SCHEMBL4722294 | 0.76 | KDM4C (0.36) | KDM4CDHFR | |
| SCHEMBL11937237 | 0.75 | DHFR (0.46) | KDM4CNPC1RAB9ANPY1RNPY2R | |
| SCHEMBL7231933 | 0.74 | NPY1R (0.54) | NPC1RAB9ANPY1RNPY2RNPY4R | |
| SCHEMBL29073288 | 0.72 | HSD11B1 (0.33) | PDE4BL3MBTL1HSD11B1 | |
| SCHEMBL4724373 | 0.71 | GAA (0.33) | KDM4CPDE4BDHFR | |
| SCHEMBL9597884 | 0.71 | KIF11 (0.36) | KIF11 | |
| SCHEMBL28641211 | 0.70 | MEN1 (0.30) | PDE4BDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012113-A1 | 3-SUBSTITUTED IMIDAZO (1,5-a) AND IMIDAZO (1,5-a)-TRIAZOLO (1,5-c) QUINOXALINES AND QUINAZOLINES WITH CNS ACTIVITY | THE UPJOHN COMPANY (US) | 1993-06-24 | — | — | WO | disclosed |