⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443375 | 0.60 | MAPT (0.31) | — | |
| Water SCHEMBL11250631 | 0.58 | — | — | |
| SCHEMBL11467922 | 0.58 | — | — | |
| SCHEMBL10361075 | 0.58 | ALDH1A1 (0.31) | — | |
| SCHEMBL9600337 | 0.57 | — | — | |
| SCHEMBL9600331 | 0.57 | — | — | |
| SCHEMBL343487 | 0.56 | — | — | |
| SCHEMBL9665495 | 0.55 | — | — | |
| SCHEMBL9335488 | 0.55 | — | — | |
| SCHEMBL7309307 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371074-A | Use of saccharin derivatives as proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1994-12-06 | — | — | US | claimed |
| EP-0542372-A1 | 2-Substituted saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1993-05-19 | — | — | EP | claimed |
| US-4950660-A | INTERMEDIATES FOR B-LACTAM ANTIBIOTICS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1990-08-21 | — | — | US | claimed |
| US-4560750-A | Cephem compounds and process for preparing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1985-12-24 | — | — | US | claimed |
| US-5773456-A | EMPHYSEMA, RHEUMATOID ARTHRITIS AND PANCREATITIS | SANOFI (FR) | 1998-06-30 | — | — | US | disclosed |
| US-5578623-A | DRUGS FOR TREATMENT OF ARTHRITIS, PANCREATITIS, CYSTIC FIBROSIS, BRONCHITIS, RESPIRATORY DISORDERS | STERLING WINTHROP INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5464852-A | Used in treatment of degenerative diseases | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |
| US-5380737-A | Enzyme inhibitors | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0542371-A1 | Saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1993-05-19 | — | — | EP | disclosed |
| CN-1020340-C | 1-carbacephalosporin antibiotics | LILLY CO ELI (US) | 1993-04-21 | — | — | CN | disclosed |
| US-4950660-A | INTERMEDIATES FOR B-LACTAM ANTIBIOTICS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1990-08-21 | — | — | US | disclosed |
| EP-0311254-A2 | Beta-lactam compound and process for production thereof | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1989-04-12 | — | — | EP | disclosed |
| US-4603129-A | Cephalosporin derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-29 | — | — | US | disclosed |
| US-4560750-A | Cephem compounds and process for preparing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1985-12-24 | — | — | US | disclosed |
| EP-0150609-A2 | Cephalosporin antibiotics | GLAXO GROUP LIMITED (GB) | 1985-08-07 | — | — | EP | disclosed |
| US-4485235-A | Process for preparing 7-α-methoxycephem compounds | MEIJI SEIKA KAISHA LTD. (JP) | 1984-11-27 | — | — | US | disclosed |
| US-4470983-A | BACTERICIDES, ANTIBIOTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |
| EP-0034760-B1 | CEPHALOSPORIN DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-30 | — | — | EP | disclosed |
| US-4325951-A | 1-Oxadethiacephalosporin derivatives and antibacterial use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 1982-04-20 | — | — | US | disclosed |
| EP-0034760-A1 | Cephalosporin derivatives, pharmaceutical compositions and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-02 | — | — | EP | disclosed |