Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | EED | O75530 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GPR183 | P32249 | 1/20 | 0.52 |
| ▸ | CCR3 | P51677 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13152011 | 0.84 | TACR3 (0.67) | TACR3HPGDGAAALDH1A1LMNA | |
| SCHEMBL18768532 | 0.82 | GAA (0.67) | HPGDGAAALDH1A1LMNARAB9A | |
| SCHEMBL5359069 | 0.80 | CCR3 (0.62) | TACR3ALDH1A1LMNARAB9AMEN1 | |
| SCHEMBL5037841 | 0.78 | TACR3 (0.64) | TACR3HPGDGAAALDH1A1LMNA | |
| SCHEMBL14263092 | 0.78 | TACR3 (0.59) | TACR3ALDH1A1MEN1KMT2ACCR3 | |
| SCHEMBL31324479 | 0.77 | TACR3 (0.62) | TACR3HPGDGAAALDH1A1LMNA | |
| SCHEMBL2236750 | 0.76 | SMN1; SMN2 (0.84) | HPGDGAAALDH1A1LMNARAB9A | |
| SCHEMBL7822101 | 0.76 | L3MBTL1 (0.60) | TACR3ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL8637987 | 0.76 | EED (0.68) | GAAALDH1A1LMNARAB9AMEN1 | |
| SCHEMBL7252710 | 0.75 | CARM1 (0.60) | MEN1KMT2ASIGMAR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190958-A | Fungicides | SHELL RESEARCH LIMITED (GB) | 1993-03-02 | — | — | US | disclosed |
| EP-0435387-A1 | Piperidine derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-07-03 | — | — | EP | disclosed |