Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316193 | 0.84 | KMT2A (0.46) | KMT2AFFAR1MMP12MMP13HTT | |
| SCHEMBL5338091 | 0.82 | KMT2A (0.45) | KMT2AFFAR1MMP12MMP13HTT | |
| SCHEMBL5317107 | 0.81 | KMT2A (0.44) | KMT2AFFAR1MMP12MMP13HTT | |
| SCHEMBL7374914 | 0.81 | KMT2A (0.72) | KMT2AFFAR1HTTFFAR4 | |
| SCHEMBL1337387 | 0.79 | FFAR1 (0.69) | FFAR1MMP12MMP13HTTFFAR4 | |
| Hydrochloric Acid SCHEMBL7956222 | 0.77 | FFAR1 (0.67) | FFAR1MMP12MMP13HTTFFAR4 | |
| SCHEMBL14183081 | 0.75 | POLB (0.59) | KMT2AMAOBMMP12MMP13HTT | |
| SCHEMBL1507376 | 0.74 | ALDH1A1 (0.57) | FFAR1MMP12MMP13HTTFFAR4 | |
| SCHEMBL7338789 | 0.73 | FFAR1 (0.53) | FFAR1MMP12MMP13HTTFFAR4 | |
| SCHEMBL29965012 | 0.73 | MAOB (0.52) | MAOBMMP12MMP13HTTNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574545-A1 | PHENYL AMIDINES DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS. | SEARLE & CO (US) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992015607-A2 | PHENYL AMIDINES DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-09-17 | — | — | WO | disclosed |