Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316193 | 0.84 | KMT2A (0.46) | KMT2ANSD2FFAR1CYP2A6MMP12 | |
| SCHEMBL9601660 | 0.82 | KMT2A (0.49) | KMT2ANSD2FFAR1MMP12MMP13 | |
| SCHEMBL5317107 | 0.81 | KMT2A (0.44) | KMT2ANSD2FFAR1CYP2A6MMP12 | |
| SCHEMBL5317404 | 0.75 | NSD2 (0.58) | KMT2ANSD2MMP2SIGMAR1 | |
| SCHEMBL5401771 | 0.75 | FFAR1 (0.39) | KMT2ANSD2FFAR1HRH3TSHR | |
| SCHEMBL4498529 | 0.74 | TSHR (0.42) | NSD2CYP2A6MMP12MMP13HRH3 | |
| SCHEMBL2339114 | 0.74 | FFAR1 (0.50) | FFAR1CYP2A6MMP12MMP13SAE1 | |
| SCHEMBL1507376 | 0.74 | ALDH1A1 (0.57) | FFAR1CYP2A6MMP12MMP13SAE1 | |
| SCHEMBL7338789 | 0.73 | FFAR1 (0.53) | FFAR1CYP2A6MMP12MMP13SAE1 | |
| SCHEMBL6298268 | 0.73 | FFAR1 (0.47) | KMT2AFFAR1CYP2A6MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |