Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343160 | 0.92 | DAO (0.37) | PGRDAOKDM4EGRIN1MPO | |
| SCHEMBL8342999 | 0.81 | GRIA1 (0.45) | PGRDAOOPRM1OPRL1KDM4E | |
| SCHEMBL8342152 | 0.80 | GRIK1 (0.36) | GRIN1GRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL8345260 | 0.80 | GRIK1 (0.34) | GRIN1GRIN2DGRIN3BGRIA1GRIA2 | |
| SCHEMBL8346146 | 0.80 | PGR (0.40) | PGRDAOOPRM1OPRL1KDM4E | |
| SCHEMBL8344983 | 0.76 | CA12 (0.40) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9601771 | 0.75 | PGR (0.57) | PGRDAOOPRM1OPRL1KDM4E | |
| SCHEMBL8345933 | 0.74 | GRIA1 (0.45) | DAOKDM4EGRIN1MPOGRIN2D | |
| SCHEMBL7349789 | 0.73 | DAO (0.44) | PGRDAOOPRM1OPRL1KDM4E | |
| SCHEMBL8343157 | 0.71 | DAO (0.37) | PGRDAOKDM4EGRIN1MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |