Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846764 | 0.83 | HIF1A (0.44) | HIF1AMAPK1KIF11ALDH1A1TSHR | |
| SCHEMBL9189254 | 0.80 | ALDH1A1 (0.52) | HIF1AMAPK1KIF11ALDH1A1KCNN4 | |
| SCHEMBL22411320 | 0.79 | KCNN4 (0.39) | HIF1AMAPK1KIF11ALDH1A1TSHR | |
| SCHEMBL7565230 | 0.77 | HIF1A (0.39) | HIF1AMAPK1KIF11ALDH1A1KCNN4 | |
| Hydrochloric Acid SCHEMBL1249575 | 0.76 | HIF1A (0.38) | HIF1AMAPK1KIF11ALDH1A1KCNN4 | |
| SCHEMBL26653428 | 0.76 | HIF1A (0.38) | HIF1AMAPK1KIF11ALDH1A1TSHR | |
| SCHEMBL6932099 | 0.76 | HIF1A (0.38) | HIF1AMAPK1KIF11ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL3839261 | 0.76 | KIF11 (0.41) | HIF1AMAPK1KIF11KCNN4CYP2C19 | |
| SCHEMBL10664452 | 0.76 | KIF11 (0.50) | HIF1AMAPK1KIF11ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1535932 | 0.74 | HIF1A (0.38) | HIF1AMAPK1KIF11KCNN4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215435-B1 | 2-OXA-ISOCEPHEM COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4831026-A | ANTIBIOTICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0215435-A1 | 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |