Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26653428 | 0.82 | HIF1A (0.38) | HIF1AMAPK1KIF11ALDH1A1TSHR | |
| SCHEMBL5846764 | 0.79 | HIF1A (0.44) | HIF1AMAPK1KIF11ALDH1A1TSHR | |
| SCHEMBL9189254 | 0.76 | ALDH1A1 (0.52) | HIF1AMAPK1KIF11ALDH1A1KCNN4 | |
| SCHEMBL9601801 | 0.76 | HIF1A (0.41) | HIF1AMAPK1KIF11ALDH1A1TSHR | |
| SCHEMBL7565230 | 0.73 | HIF1A (0.39) | HIF1AMAPK1KIF11ALDH1A1KCNN4 | |
| SCHEMBL9516007 | 0.72 | HCAR2 (0.65) | MAPK1ALDH1A1HCAR2LMNAPOLB | |
| Hydrochloric Acid SCHEMBL3839261 | 0.71 | KIF11 (0.41) | HIF1AMAPK1KIF11KCNN4CYP2C19 | |
| SCHEMBL22411320 | 0.71 | KCNN4 (0.39) | HIF1AMAPK1KIF11ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL1249575 | 0.71 | HIF1A (0.38) | HIF1AMAPK1KIF11ALDH1A1NPSR1 | |
| SCHEMBL10664452 | 0.71 | KIF11 (0.50) | HIF1AMAPK1KIF11ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645548-B1 | METHODS FOR PREPARING BILE ACIDS | MEDYTOX INC (KR) | 2023-11-29 | — | — | EP | disclosed |
| US-20220009957-A1 | Methods for Preparing Bile Acids | MEDYTOX INC. (KR) | 2022-01-13 | — | — | US | disclosed |
| US-11161872-B2 | Methods for preparing bile acids | MEDYTOX INC. (KR) | 2021-11-02 | — | — | US | disclosed |
| US-20200369712-A1 | METHODS FOR PREPARING BILE ACIDS | WUXI APPTEC (SHANGHAI) CO., LTD. (CN) | 2020-11-26 | — | — | US | disclosed |
| EP-3645548-A1 | METHODS FOR PREPARING BILE ACIDS | Medytox Inc. (KR) | 2020-05-06 | — | — | EP | disclosed |
| WO-2019024920-A1 | METHODS FOR PREPARING BILE ACIDS | MEDYTOX INC. (KR) | 2019-02-07 | — | — | WO | disclosed |
| EP-1363869-B1 | PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES | WEYLCHEM LAMOTTE (FR) | 2015-04-08 | — | — | EP | disclosed |
| EP-1363869-A2 | PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES | Clariant (France) S.A. (FR) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002067847-A2 | PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES | CLARIANT (FRANCE) (FR) | 2002-09-06 | — | — | WO | disclosed |
| EP-0665224-A1 | PYRIMIDINE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-4021479-A | ANTIPHLOGISTICS AND ANTIPROLIFERATIVES | BOEHRINGER INGELHEIM GMBH (DT) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009957-A1 | Methods for Preparing Bile Acids | DHCR7, CYP46A1, CYP27A1 | HIF1A 4682/4885MAPK1 2189/4885KIF11 961/4885 |
| US-20200369712-A1 | METHODS FOR PREPARING BILE ACIDS | DHCR7, CYP46A1, CYP27A1 | HIF1A 4682/4885MAPK1 2189/4885KIF11 961/4885 |
| US-11161872-B2 | Methods for preparing bile acids | DHCR7, CYP46A1, CYP27A1 | HIF1A 4682/4885MAPK1 2189/4885KIF11 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.